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<h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Gregory Petsko</span></h1>
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<p><b>Gregory Anthony Petsko</b> (* <a href="7._August" title="7. August">7. August</a> <a href="1948" title="1948">1948</a> in <a href="Washington%2C_D.C." title="Washington, D.C.">Washington, D.C.</a>) ist ein <a href="Vereinigte_Staaten" title="Vereinigte Staaten">US-amerikanischer</a> <a href="Biochemie" title="Biochemie">Biochemiker</a> und <a href="Neurowissenschaften" title="Neurowissenschaften">Neurowissenschaftler</a> an der <a href="Cornell_University" title="Cornell University">Cornell University</a> und dem <a href="Weill_Cornell_Medical_College" title="Weill Cornell Medical College">Weill Cornell Medical College</a> in <a href="New_York_City" title="New York City">New York City</a>. Gemeinsam mit seiner langjährigen Forschungspartnerin Dagmar Ringe gilt Petsko als Begründer des Wissenschaftsgebiets der „Strukturneurologie“ als Querschnittsgebiet zwischen <a href="Strukturbiologie" title="Strukturbiologie">Strukturbiologie</a> und <a href="Neurologie" title="Neurologie">Neurologie</a>.
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<div class="mw-heading mw-heading2"><h2 id="Leben_und_Wirken">Leben und Wirken</h2></div>
<p>Petsko erwarb 1970 an der <a href="Princeton_University" title="Princeton University">Princeton University</a> einen <a href="Bachelor" title="Bachelor">Bachelor</a> in <a href="Chemie" title="Chemie">Chemie</a> und 1973 bei <a href="David_C._Phillips" title="David C. Phillips">David C. Phillips</a> an der <a href="Oxford_University" class="mw-redirect" title="Oxford University">Oxford University</a> einen <a href="Ph.D." title="Ph.D.">Ph.D.</a> in molekularer <a href="Biophysik" title="Biophysik">Biophysik</a>. Als <a href="Postdoktorand" class="mw-redirect" title="Postdoktorand">Postdoktorand</a> arbeitete er bei Pierre Douzou in Paris. Eine erste Professur <i>(Assistant Professor)</i> erhielt er an der <i><a href="Wayne_State_University" title="Wayne State University">Wayne State University</a> School of Medicine</i>, bevor er 1979 als <i>Associate Professor</i> für Chemie an das <a href="Massachusetts_Institute_of_Technology" title="Massachusetts Institute of Technology">Massachusetts Institute of Technology</a> wechselte und dort schließlich eine ordentliche Professur erhielt. 1990 wechselte er als Professor für Biochemie und Chemie an die <a href="Brandeis_University" title="Brandeis University">Brandeis University</a>, wo er von 1994 bis 2006 Direktor des <i>Rosenstiel Basic Medical Sciences Research Center</i> war und von 2008 bis 2011 die Abteilung für Biochemie leitete. 2014 ging Petsko als Professor für <a href="Neurologie" title="Neurologie">Neurologie</a> und <a href="Neurowissenschaften" title="Neurowissenschaften">Neurowissenschaften</a> an das <a href="Weill_Cornell_Medical_College" title="Weill Cornell Medical College">Weill Cornell Medical College</a>. Gleichzeitig hat er eine Professur für <a href="Medizintechnik" title="Medizintechnik">Medizintechnik</a> <i>(Biomedical engineering)</i> an der <a href="Cornell_University" title="Cornell University">Cornell University</a> inne.
</p><p>Gregory Petsko hat über viele Jahre die Methoden der <a href="Kristallographie" title="Kristallographie">Kristallographie</a> verfeinert und auf die zeitabhängige dreidimensionale Beobachtung von <a href="Enzymsubstratkomplex" class="mw-redirect" title="Enzymsubstratkomplex">Enzym-Substrat-Komplexen</a> beziehungsweise Enzym-<a href="Stoffwechselintermediat" title="Stoffwechselintermediat">Intermediat</a>-Komplexen ausgedehnt. Er betreibt heute (Stand 2017) <a href="Grundlagenforschung" title="Grundlagenforschung">Grundlagenforschung</a> auf dem Gebiet der Beziehung zwischen <a href="Protein" title="Protein">Proteinen</a>, <a href="Proteinstruktur" title="Proteinstruktur">Proteinstruktur</a> und -funktion und <a href="Neurodegenerative_Erkrankung" title="Neurodegenerative Erkrankung">neurodegenerativen Erkrankungen</a>. Er erforscht mit Hilfe <a href="Genetik" title="Genetik">genetischer</a> und <a href="Strukturbiologie" title="Strukturbiologie">strukturbiologischer</a> Techniken (insbesondere <a href="Proteinkristallographie" class="mw-redirect" title="Proteinkristallographie">Proteinkristallographie</a>) sowie struktur-vermittelter <a href="Pharmaforschung" title="Pharmaforschung">Pharmaforschung</a> (<a href="Wirkstoffdesign" title="Wirkstoffdesign">Wirkstoffdesign</a>) neue Ziele zur medikamentösen Behandlung neurodegenerativer Erkrankungen.
</p><p>Petsko ist mit der Immunologin <a href="Laurie_H._Glimcher" title="Laurie H. Glimcher">Laurie H. Glimcher</a> verheiratet.
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<div class="mw-heading mw-heading2"><h2 id="Auszeichnungen_(Auswahl)"><span id="Auszeichnungen_.28Auswahl.29"></span>Auszeichnungen (Auswahl)</h2></div>
<ul><li>1978 <a href="Sloan_Research_Fellowship" title="Sloan Research Fellowship">Sloan Research Fellow</a><sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></li>
<li>1987 <a href="Pfizer_Award_in_Enzyme_Chemistry" title="Pfizer Award in Enzyme Chemistry">Pfizer Award in Enzyme Chemistry</a><sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></li>
<li>1991 <a href="Max-Planck-Forschungspreis" title="Max-Planck-Forschungspreis">Max-Planck-Forschungspreis</a></li>
<li>1995 Mitglied der <a href="National_Academy_of_Sciences" title="National Academy of Sciences">National Academy of Sciences</a><sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup></li>
<li>2001 Mitglied des <i>Institute of Medicine</i> (heute <a href="National_Academy_of_Medicine" title="National Academy of Medicine">National Academy of Medicine</a>)<sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup></li>
<li>2002 Mitglied der <a href="American_Academy_of_Arts_and_Sciences" title="American Academy of Arts and Sciences">American Academy of Arts and Sciences</a><sup id="cite_ref-5" class="reference"><a href="#cite_note-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup></li>
<li>2004 <i>Fellow</i> der <a href="American_Association_for_the_Advancement_of_Science" title="American Association for the Advancement of Science">American Association for the Advancement of Science</a></li>
<li>2008–2010 Präsident der <a href="American_Society_for_Biochemistry_and_Molecular_Biology" title="American Society for Biochemistry and Molecular Biology">American Society for Biochemistry and Molecular Biology</a><sup id="cite_ref-6" class="reference"><a href="#cite_note-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup></li>
<li>2010 Mitglied der <a href="American_Philosophical_Society" title="American Philosophical Society">American Philosophical Society</a><sup id="cite_ref-7" class="reference"><a href="#cite_note-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup></li>
<li>2011 <a href="Ehrendoktorat" class="mw-redirect" title="Ehrendoktorat">Ehrendoktorat</a> der <a href="Dalhousie_University" title="Dalhousie University">Dalhousie University</a> (Kanada)<sup id="cite_ref-8" class="reference"><a href="#cite_note-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup></li>
<li>2023 <a href="National_Medal_of_Science" title="National Medal of Science">National Medal of Science</a></li></ul>
<div class="mw-heading mw-heading2"><h2 id="Weblinks">Weblinks</h2></div>
<ul><li><a rel="nofollow" class="external text" href="http://vivo.med.cornell.edu/display/cwid-gpetsko"><i>Gregory Petsko – Arthur J. Mahon Professor of Neuroscience</i></a> und <a rel="nofollow" class="external text" href="http://appel.weill.cornell.edu/petsko-laboratory"><i>Petsko Laboratory</i></a> beim <a href="Weill_Cornell_Medical_College" title="Weill Cornell Medical College">Weill Cornell Medical College</a> (cornell.edu)</li>
<li><a rel="nofollow" class="external text" href="https://www.coursehero.com/file/27653886/petskodoc/">CURRICULUM VITAE Gregory A Petsko</a></li>
<li><a rel="nofollow" class="external text" href="https://academictree.org/chemistry/peopleinfo.php?pid=59284">Informationen</a> zu und <a rel="nofollow" class="external text" href="https://academictree.org/chemistry/tree.php?pid=59284">akademischer Stammbaum</a> von <i>Gregory Petsko</i> bei academictree.org<span class="editoronly" style="display:none;"></span></li></ul>
<div class="mw-heading mw-heading2"><h2 id="Einzelnachweise">Einzelnachweise</h2></div>
<ol class="references">
<li id="cite_note-1"><span class="mw-cite-backlink"><a href="#cite_ref-1">↑</a></span> <span class="reference-text"><span class="cite"><a rel="nofollow" class="external text" href="https://sloan.org/fellows-database"><i>Past Fellows.</i></a> Alfred P. Sloan Foundation,<span class="Abrufdatum"> abgerufen am 9. November 2022</span>.</span><span style="display: none;" class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rfr_id=info%3Asid%2Fde.wikipedia.org%3AGregory+Petsko&rft.title=Past+Fellows&rft.description=Past+Fellows&rft.identifier=https%3A%2F%2Fsloan.org%2Ffellows-database&rft.publisher=Alfred+P.+Sloan+Foundation"> </span></span>
</li>
<li id="cite_note-2"><span class="mw-cite-backlink"><a href="#cite_ref-2">↑</a></span> <span class="reference-text"><a rel="nofollow" class="external text" href="https://www.divbiolchem.org/s/pfizerawardees_final.pdf">Pfizer Award in Enzyme Chemistry</a> (PDF, 158 kB) bei der <i>Division of Biological Chemistry</i> der <a href="American_Chemical_Society" title="American Chemical Society">American Chemical Society</a> (dicbiolchem.org); abgerufen am 30. Mai 2025.</span>
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<li id="cite_note-3"><span class="mw-cite-backlink"><a href="#cite_ref-3">↑</a></span> <span class="reference-text"><span class="cite"><a rel="nofollow" class="external text" href="https://www.nasonline.org/directory-entry/gregory-a-petsko-qly6w5/"><i>Gregory Petsko.</i></a> In: <i>nasonline.org.</i> <a href="National_Academy_of_Sciences" title="National Academy of Sciences">National Academy of Sciences</a>,<span class="Abrufdatum"> abgerufen am 13. Juni 2025</span> (englisch).</span><span style="display: none;" class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rfr_id=info%3Asid%2Fde.wikipedia.org%3AGregory+Petsko&rft.title=Gregory+Petsko&rft.description=Gregory+Petsko&rft.identifier=https%3A%2F%2Fwww.nasonline.org%2Fdirectory-entry%2Fgregory-a-petsko-qly6w5%2F&rft.publisher=%5B%5BNational+Academy+of+Sciences%5D%5D&rft.language=en"> </span></span>
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<li id="cite_note-4"><span class="mw-cite-backlink"><a href="#cite_ref-4">↑</a></span> <span class="reference-text"><span class="cite"><a rel="nofollow" class="external text" href="https://nam.edu/member/gregory-a-petsko/"><i>Gregory A. Petsko.</i></a> In: <i>nam.edu.</i> <a href="National_Academy_of_Sciences" title="National Academy of Sciences">National Academy of Sciences</a>,<span class="Abrufdatum"> abgerufen am 16. August 2025</span> (englisch).</span><span style="display: none;" class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rfr_id=info%3Asid%2Fde.wikipedia.org%3AGregory+Petsko&rft.title=Gregory+A.+Petsko&rft.description=Gregory+A.+Petsko&rft.identifier=https%3A%2F%2Fnam.edu%2Fmember%2Fgregory-a-petsko%2F&rft.publisher=%5B%5BNational+Academy+of+Sciences%5D%5D&rft.language=en"> </span></span>
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<li id="cite_note-5"><span class="mw-cite-backlink"><a href="#cite_ref-5">↑</a></span> <span class="reference-text"><span class="cite"><a rel="nofollow" class="external text" href="https://www.amacad.org/multimedia/pdfs/publications/bookofmembers/ChapterP.pdf"><i>Book of Members 1780–present, Chapter P.</i></a> (PDF; 1,1 kB) In: <i>amacad.org.</i> <a href="American_Academy_of_Arts_and_Sciences" title="American Academy of Arts and Sciences">American Academy of Arts and Sciences</a>,<span class="Abrufdatum"> abgerufen am 2. November 2021</span> (englisch).</span><span style="display: none;" class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rfr_id=info%3Asid%2Fde.wikipedia.org%3AGregory+Petsko&rft.title=Book+of+Members+1780%E2%80%93present%2C+Chapter+P&rft.description=Book+of+Members+1780%E2%80%93present%2C+Chapter+P&rft.identifier=https%3A%2F%2Fwww.amacad.org%2Fmultimedia%2Fpdfs%2Fpublications%2Fbookofmembers%2FChapterP.pdf&rft.publisher=%5B%5BAmerican+Academy+of+Arts+and+Sciences%5D%5D&rft.language=en"> </span></span>
</li>
<li id="cite_note-6"><span class="mw-cite-backlink"><a href="#cite_ref-6">↑</a></span> <span class="reference-text"><span class="cite"><a rel="nofollow" class="external text" href="https://www.asbmb.org/about/past-presidents"><i>Past presidents.</i></a> In: <i>asbmb.org.</i><span class="Abrufdatum"> Abgerufen am 30. Mai 2025</span> (englisch).</span><span style="display: none;" class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rfr_id=info%3Asid%2Fde.wikipedia.org%3AGregory+Petsko&rft.title=Past+presidents&rft.description=Past+presidents&rft.identifier=https%3A%2F%2Fwww.asbmb.org%2Fabout%2Fpast-presidents&rft.language=en"> </span></span>
</li>
<li id="cite_note-7"><span class="mw-cite-backlink"><a href="#cite_ref-7">↑</a></span> <span class="reference-text"><span class="cite"><a rel="nofollow" class="external text" href="https://search.amphilsoc.org/memhist/search?creator=petsko"><i>Dr. Gregory A. Petsko.</i></a> In: <i>amphilsoc.org.</i><span class="Abrufdatum"> Abgerufen am 16. Juli 2025</span> (englisch).</span><span style="display: none;" class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rfr_id=info%3Asid%2Fde.wikipedia.org%3AGregory+Petsko&rft.title=Dr.+Gregory+A.+Petsko&rft.description=Dr.+Gregory+A.+Petsko&rft.identifier=https%3A%2F%2Fsearch.amphilsoc.org%2Fmemhist%2Fsearch%3Fcreator%3Dpetsko&rft.language=en"> </span></span>
</li>
<li id="cite_note-8"><span class="mw-cite-backlink"><a href="#cite_ref-8">↑</a></span> <span class="reference-text"><span class="cite"><a rel="nofollow" class="external text" href="https://www.dal.ca/convocation/history_traditions/honorary_degree_recipients/hon_degree_2010_2019.html"><i>2010 ‑ 2019 Honorary Degree Recipients.</i></a> In: <i>dal.ca.</i> <a href="Dalhousie_University" title="Dalhousie University">Dalhousie University</a>,<span class="Abrufdatum"> abgerufen am 16. August 2025</span> (englisch).</span><span style="display: none;" class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rfr_id=info%3Asid%2Fde.wikipedia.org%3AGregory+Petsko&rft.title=2010+%E2%80%91+2019+Honorary+Degree+Recipients&rft.description=2010+%E2%80%91+2019+Honorary+Degree+Recipients&rft.identifier=https%3A%2F%2Fwww.dal.ca%2Fconvocation%2Fhistory_traditions%2Fhonorary_degree_recipients%2Fhon_degree_2010_2019.html&rft.publisher=%5B%5BDalhousie+University%5D%5D&rft.language=en"> </span></span>
</li>
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Normdaten (Person): <a href="Library_of_Congress_Control_Number" title="Library of Congress Control Number">LCCN</a>: <span class="-print"><a rel="nofollow" class="external text" href="https://id.loc.gov/authorities/no98014393">no98014393</a></span> | <a href="Web_NDL_Authorities" title="Web NDL Authorities">NDL</a>: <span class="-print"><a rel="nofollow" class="external text" href="https://id.ndl.go.jp/auth/ndlna/01017233">01017233</a></span> | <a href="Virtual_International_Authority_File" title="Virtual International Authority File">VIAF</a>: <span class="-print"><a rel="nofollow" class="external text" href="https://viaf.org/viaf/39628851/">39628851</a></span> | </div>
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